ANGIOTENSIN-CONVERTING ENZYME 2 POTENTIATES SARS-COV-2 INFECTION BY ANTAGONIZING TYPE I INTERFERON INDUCTION AND ITS DOWN-STREAM SIGNALING PATHWAY

Angiotensin-Converting Enzyme 2 Potentiates SARS-CoV-2 Infection by Antagonizing Type I Interferon Induction and Its Down-Stream Signaling Pathway

ABSTRACT The innate interferon (IFN) response constitutes the first line of host defense against viral infections.It has been shown that IFN-I/III treatment could effectively contain severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication in vitro.However, how SARS-CoV-2 survives through the innate antiviral mechanism remains to be

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Acute Low Force Electrically Induced Exercise Modulates Post Prandial Glycemic Markers in People with Spinal Cord Injury

Regular exercise involves daily muscle contractions helping metabolize up to 70% of daily ingested glucose.Skeletal muscle increases glucose uptake through two distinct pathways: insulin signaling pathway and muscle contraction mediated AMPK pathway.People with paralysis are unable to contract their muscles which atrophy, transform into insulin res

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